![]() ![]() 31 (77.5%) and 19 pts (47.5%) received ≥ 2 and 3 prior lines of therapy, respectively. ResultsĪs of July 17, 2019, 40 pts with NSCLC (22 female, median age: 68.0 years ) were enrolled. KRAS p.G12C mutant allele frequency (MAF) and PD-L1 level were examined. Primary endpoint is safety key secondary endpoints include objective response rate (ORR), disease control rate (DCR), duration of response (DOR), and progression-free survival (PFS). Key eligibility criteria include KRAS p.G12C mutation and prior systemic anticancer treatment (tx). Here, we present durability of clinical benefit and biomarker data in pts with NSCLC. The phase 1 trial of sotorasib, a KRAS G12C inhibitor, demonstrated a favorable safety profile and preliminary antitumor activity in pts with advanced solid tumors harboring KRAS p.G12C. ![]()
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![]() Next steps: We are working on a resolution and will provide an update in an upcoming release. If your app is unable to use DSN, the app will need to be modified to allow for DSN or to use a newer ODBC driver than Microsoft ODBC SQL Server Driver (sqlsrv32.dll).Note: We recommend the latest version of Microsoft ODBC Driver 17 for SQL Server, as it is more compatible with apps currently using the legacy Microsoft ODBC SQL Server Driver (sqlsrv32.dll) than Microsoft ODBC Driver 18 for SQL Server. If your app is already using or able to use Data Source Name (DSN) to select ODBC connections, install Microsoft ODBC Driver 17 for SQL Server and select it for use with your app using DSN.Workaround: To mitigate this issue, you can do one of the following: If you are unsure if you are using any affected apps, open any apps which use a database and then open Command Prompt (select Start then type command prompt and select it) and type the following command: tasklist /m sqlsrv32.dll This issue might occur when calling SQLBindCol function before SQLFetch or calling SQLGetData function after SQLFetch and when a value of 0 (zero) is given for the ‘BufferLength’ argument for fixed datatypes larger than 4 bytes (such as SQL_C_FLOAT). 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